Importance of moderate-to-vigorous physical activity during the COVID-19 pandemic: a systematic review and meta-analysis.

Moderate-to-vigorous physical activity (MVPA) has been shown to have a favorable effect on many diseases as a complementary therapy and is a critical component of healthy living. During the pandemic era, physical activity has been promoted for resistance against coronavirus disease 2019 (COVID-19). However, there is scarce evidence on whether MVPA could reduce the infectivity and susceptibility to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The objective of this meta-analysis was to determine the effect of MVPA on morbidity, mortality, and duration of hospitalization in COVID-19 patients. We performed a comprehensive search of five online databases for eligible studies up to September 9, 2021. Meta-analyses were conducted to determine the association between MVPA and COVID-19-related morbidity, hospitalization, and mortality. The odds ratio (OR) was applied as the summary statistic for the primary outcomes. Secondary analyses were conducted to evaluate the difference in the metabolic equivalent of tasks (METs) between the outcome and non-outcome groups with the mean difference as the pooled effect. This meta-analysis included eight observational studies. We found that MVPA significantly reduced the odds of contracting SARS-CoV-2 infection (OR=0.88; 95% confidence interval [CI] = 0.85-0.92), hospitalization (OR=0.56; 95% CI=0.35-0.92), and mortality (OR=0.42; 95% CI=0.21-0.81) due to COVID-19 compared to no physical activity. METs≥500 min/week were linked to decreased morbidity and mortality of COVID-19 (OR=0.94 [95% CI=0.90-0.98]; OR=0.56 [95% CI=0.38-0.83]). COVID-19 patients with MVPA demonstrated a lower risk of COVID-19-related morbidity, hospitalization, and mortality compared to those who were less active, highlighting the importance of an active lifestyle despite the pandemic situation where such activities are limited.

Maximizing millennial students’ role in combating COVID-19 hoaxes and myths

Since the outbreak of Corona Disease-19 (COVID-19) spreads all over the world various ways of health attempts have been conducted. However overflowed information intertwines with mis/disinformation could raise public anxiety and stigma-related diseases. We aimed to assess the help of the young generation of millennials and Gen-Z who are active college students in debunking hoaxes and myths of COVID-19 into their community. Method: The selected students were given a short course on COVID-19 basic information prevention and circulated myths. Later they become ambassadors and actively educated via offline and online platforms. The impact of outspread information on audiences was investigated through a qualitative survey. Result: The knowledge of students was measured by pre- and post-test within the short course. Prior knowledge showed the least understanding part was prevention and myth of COVID-19. There was a significant improvement of knowledge in post-test after receiving seminar (p=0.0002). There were 97 respondents who filled the online survey that predominantly in young adulthood age. Respondents’ insight was enhanced, and they likely intend to spread the actual information to their surroundings. Conclusion: Appointing student as the spokesperson for health education can raise their social responsibility. Clarifying misinformation and health behavior could be more influential within the same sharing community. In addition, the use of various online platforms could efficiently reach massive target especially young ages.

THE IMPROVEMENT OF COMMUNITY KNOWLEDGE, ATTITUDES AND PRACTICES AFTER COVID-19 SOCIALIZATION

This study determined community knowledge, attitudes, and practices after COVID-19 socialization in Rambipuji and Suci Village, Jember District, East Java, Indonesia. This study used the analytic observational design study. As many as 40 people were given socialization about COVID-19 by gathering and online. The questionnaires were completed in two parts included before-socialization and after-socialization. The questionnaire data were analyzed descriptively by calculating frequency, percentage, and inferential statistics by t-test, Spearman correlation, and chi-square test. The data analysis used IBM SPSS version 23 software. The mean and standard deviation of percentage of knowledge pre-test, knowledge post-test, high attitude, moderate attitude, low attitude, very high practice, high practice, sufficient practice, and low practice were 58.33 ± 30.97, 77.70 ± 22.52, 62.5±21.7, 31±22.2, 6.5±17.1, 65±13.8, 32.3±13.8, 1.25±2.4, 1.25±1.8, respectively. Knowledge pre-test and post-test correlated 0.819 (p=0.001) and a t-test with p=0.003. Attitudes and practices correlated with p=0.001. Socialization of COVID-19 was useful to improve the community knowledge, attitudes, and practices in Rambipuji and Suci Village, Jember District, East Java, Indonesia that could prevent the transmission and inhibit the spread of the COVID-19 pandemic in Indonesia. Furthermore, continuous encouragement of COVID-19 socialization in wide areas was recommended. (English) [ABSTRACT FROM AUTHOR] Penelitian ini bertujuan untuk mengetahui pengetahuan, sikap, dan perilaku masyarakat setelah sosialisasi COVID-19 di Desa Rambipuji dan Suci, Kabupaten Jember, Jawa Timur, Indonesia. Penelitian ini menggunakan desain penelitian observasional analitik. Sebanyak 40 orang diberikan sosialisasi tentang COVID-19 secara tatap muka (luring) dan daring. Kuesioner diisi dalam dua sesi yaitu sebelum sosialisasi dan setelah sosialisasi. Data kuesioner dianalisis secara deskriptif dengan menghitung frekuensi, persentase dan statistik inferensial dengan uji-t, korelasi spearman dan uji chi square. Analisis data menggunakan perangkat lunak IBM SPSS versi 23. Rerata dan standar deviasi persentase pengetahuan sebelum test, pengetahuan setelah test, sikap tinggi, sikap sedang, sikap rendah, perilaku sangat tinggi, perilaku tinggi, perilaku cukup, dan perilaku rendah secara berturut-turut adalah 58,33 ± 30,97, 77,70 ± 22,52, 62,5 ± 21.7, 31 ± 22.2, 6.5 ± 17.1, 65 ± 13.8, 32.3 ± 13.8, 1.25 ± 2.4, 1.25 ± 1.8. Pengetahuan sebelum test dan setelah test memiliki korelasi 0,819 (p = 0,001) dan t-test dengan p = 0,003. Sikap dan perilaku memiliki korelasi dengan p = 0,001. Sosialisasi COVID-19 bermanfaat untuk meningkatkan pengetahuan, sikap, dan masyarakat masyarakat di Desa Rambipuji dan Suci, Kabupaten Jember, Jawa Timur, Indonesia yang dapat mencegah penularan dan menghambat penyebaran pandemi COVID-19 di Indonesia. Selain itu, sosialisasi COVID-19 terus didorong di berbagai wilayah. (Indonesian) [ABSTRACT FROM AUTHOR] Copyright of Folia Medica Indonesiana is the property of Folia Medica Indonesiana and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Meta-analysis of cardiac markers for predictive factors on severity and mortality of COVID-19.

OBJECTIVES: Previous observational studies have suggested that increased cardiac markers are commonly found in COVID-19. This study aimed to determine the relationship between several cardiac markers and the severity/mortality of COVID-19 patients. METHODS: Several cardiac markers were analysed in this meta-analysis. RevMan 5.4 was used to provide pooled estimates for standardised mean difference (SMD) with 95% confidence intervals. RESULTS: Twenty-nine clinical studies were included in this meta-analysis. Significantly higher CK-MB (0.64, 95% CI = 0.19-1.09), PCT (0.47, 95% CI = 0.26-0.68), NT-proBNP (1.90, 95% CI = 1.63-2.17), BNP (1.86, 95% CI = 1.63-2.09), and d-dimer (1.30, 95% CI = 0.91-1.69) were found in severe compared with non-severe COVID-19. Significantly higher CK-MB (3.84, 95% CI = 0.62-7.05), PCT (1.49, 95% CI = 0.86-2.13), NT-proBNP (4.66, 95% CI = 2.42-6.91), BNP (1.96, 95% CI = 0.78-3.14), troponin (1.64 (95% CI = 0.83-2.45), and d-dimer (2.72, 95% CI = 2.14-3.29) were found in those who died from compared with survivors of COVID-19. CONCLUSIONS: High CK-MB, PCT, NT-proBNP, BNP, and d-dimer could be predictive markers for severity of COVID-19, while high CK-MB, PCT, NT-proBNP, BNP, troponin, and d-dimer could be predictive markers for survival of COVID-19 patients.